Aged garlic extract

Also known as AGE garlic, kyolic.

Last reviewed October 9, 2026 · Jump to references

What is Aged garlic extract?

In plain words

Aged garlic extract is made by aging garlic, which changes many of its sulfur-containing substances. The body absorbs some of these substances, breaks them down, and removes their breakdown products. Researchers study it mainly for effects on blood pressure and heart health, but evidence that it prevents heart attacks or strokes is not established. It may increase bleeding risk, especially when combined with blood-thinning medicines.

Technical definition

Aged garlic extract is a botanical preparation produced by aging Allium sativum bulbs, commonly in an aqueous ethanol solution, yielding a mixture enriched in stable, water-soluble organosulfur compounds such as S-allyl cysteine. It has no single established molecular target; research examines effects on redox signaling, nitric oxide availability, and platelet activation. It is marketed as a dietary supplement, not an FDA-approved treatment for disease.

Educational information only. This page does not provide medical advice or determine whether a supplement is appropriate for you. Review supplements with a qualified healthcare professional, especially if you take medication, are pregnant, have surgery scheduled, or have a chronic medical condition.

Important cautions

Bleeding considerationsmoderate concern
Garlic preparations may add to the effects of anticoagulant and antiplatelet medicines. Review with a clinician before use.
Disclose before surgerymoderate concern
Inform surgical and dental teams about garlic supplements.

Discuss with a clinician if any of these apply

Bleeding disorders or anticoagulants
Upcoming surgery

Evidence by use

Each use is rated on its own. There is no single overall effectiveness score.