Beta-glucans

Also known as beta glucan, yeast beta glucan, oat beta glucan.

Last reviewed October 9, 2026 · Jump to references

What is Beta-glucans?

In plain words

Beta-glucans are types of fiber found in oats, barley, yeast, and mushrooms. The body does not fully digest them; some form a gel in the gut, and gut bacteria break down part of them. Researchers study cereal forms for cholesterol and blood sugar effects, and yeast and mushroom forms for effects on immune defenses. Evidence is stronger for the cholesterol benefits of oat and barley forms than for broad immune-health claims.

Technical definition

Beta-glucans are glucose polysaccharides found in cereal, yeast, and fungal cell walls; oats and barley contain mainly β-(1→3)/(1→4) linkages, whereas yeast and fungal forms typically contain β-(1→3) backbones with β-(1→6) branches. Cereal beta-glucans form viscous solutions in the gut that influence bile acid handling and nutrient absorption, while certain yeast and fungal beta-glucans bind immune receptors such as Dectin-1. They are marketed as food ingredients and supplements, and qualifying oat and barley products may carry authorized cholesterol-related health claims in some jurisdictions.

Educational information only. This page does not provide medical advice or determine whether a supplement is appropriate for you. Review supplements with a qualified healthcare professional, especially if you take medication, are pregnant, have surgery scheduled, or have a chronic medical condition.

Evidence by use

Each use is rated on its own. There is no single overall effectiveness score.