Black-seed oil

Also known as nigella sativa, black cumin oil, black seed.

Last reviewed October 9, 2026 · Jump to references

What is Black-seed oil?

In plain words

Black-seed oil comes from the seeds of the Nigella sativa plant. The body breaks down its fats for energy and for building cell parts. Researchers study it for possible effects on inflammation, blood sugar, and cholesterol, but human studies are generally small and do not establish it as a proven treatment.

Technical definition

Black-seed oil is a mixture of lipids extracted from Nigella sativa seeds, composed largely of triglycerides containing linoleic and oleic acids, with minor constituents such as thymoquinone. It has no single established molecular target; preclinical studies of thymoquinone suggest effects on inflammatory signaling, including NF-κB, and cellular oxidative-stress responses. It is marketed as a dietary supplement and is not FDA-approved to treat disease.

Educational information only. This page does not provide medical advice or determine whether a supplement is appropriate for you. Review supplements with a qualified healthcare professional, especially if you take medication, are pregnant, have surgery scheduled, or have a chronic medical condition.

Evidence by use

Each use is rated on its own. There is no single overall effectiveness score.