D-chiro-inositol

Also known as DCI, d chiro inositol.

Last reviewed October 9, 2026 · Jump to references

What is D-chiro-inositol?

In plain words

D-chiro-inositol is a sugar-like substance that the body makes from another form of inositol. The body uses it in signals that help insulin regulate blood sugar. Researchers study it for blood sugar control and polycystic ovary syndrome (PCOS), a condition that affects hormones and ovulation. Studies suggest possible benefits, but strong evidence and long-term safety data remain limited.

Technical definition

D-chiro-inositol (DCI) is a cyclitol, a six-carbon cyclic polyol and stereoisomer of myo-inositol, from which it is produced by enzymatic epimerization in the body. It participates in inositol-containing signaling molecules implicated in insulin action and glucose metabolism, rather than acting as a direct insulin-receptor agonist. In the United States, DCI is marketed as a dietary supplement, not an FDA-approved treatment for disease.

Educational information only. This page does not provide medical advice or determine whether a supplement is appropriate for you. Review supplements with a qualified healthcare professional, especially if you take medication, are pregnant, have surgery scheduled, or have a chronic medical condition.

Evidence by use

Each use is rated on its own. There is no single overall effectiveness score.