Manganese

Also known as manganese sulfate.

Last reviewed October 9, 2026 · Jump to references

What is Manganese?

In plain words

Manganese is a mineral the body needs in small amounts. The body uses it to process nutrients, build bone and connective tissue, and help protect cells from damage. Researchers study its role in metabolism, bone health, and brain function. Too much manganese can harm the brain and nervous system.

Technical definition

Manganese is an essential trace mineral and chemical element (Mn); manganese sulfate is a salt that supplies manganese ions. It functions as an enzyme cofactor, supporting mitochondrial manganese superoxide dismutase, arginase, and enzymes involved in metabolism and connective-tissue formation. Manganese is available in dietary supplements, which in the United States are not FDA-approved for safety and effectiveness before marketing.

Educational information only. This page does not provide medical advice or determine whether a supplement is appropriate for you. Review supplements with a qualified healthcare professional, especially if you take medication, are pregnant, have surgery scheduled, or have a chronic medical condition.

Evidence by use

Each use is rated on its own. There is no single overall effectiveness score.