Olive-leaf extract
Also known as oleuropein, olive leaf.
Last reviewed October 9, 2026 · Jump to references
What is Olive-leaf extract?
In plain words
Olive-leaf extract is made from olive tree leaves and contains plant compounds such as oleuropein. The body breaks these compounds down and processes them before clearing them. Researchers study the extract for possible effects on blood pressure, blood sugar, and cholesterol. Human studies are limited, and the extract may interact with medicines that lower blood pressure or blood sugar.
Technical definition
Olive-leaf extract is a botanical preparation from the leaves of Olea europaea containing polyphenols, notably oleuropein, a secoiridoid glycoside, and hydroxytyrosol. It has no single established molecular target; laboratory research suggests effects on oxidative stress, inflammatory signaling, and vascular function, while oleuropein is metabolized in part to hydroxytyrosol and related compounds. In the United States, it is marketed as a dietary supplement rather than an FDA-approved treatment for disease.
Educational information only. This page does not provide medical advice or determine whether a supplement is appropriate for you. Review supplements with a qualified healthcare professional, especially if you take medication, are pregnant, have surgery scheduled, or have a chronic medical condition.
Evidence by use
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Complete Research Guide
Open each section for the available evidence. Gaps are stated rather than inferred.
Overview
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Structure & Properties
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How It Works
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Human Research
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Laboratory Research
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Processing & Interactions
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Safety & Precautions
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Administration & Studied Formulations
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Applications & Related Therapies
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Cases, Considerations & Ethics
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