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Peppermint oil

Also known as enteric peppermint oil, mentha piperita.

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Last reviewed October 9, 2026 · Jump to references

What is Peppermint oil?

In plain words

Peppermint oil is a concentrated oil from the peppermint plant. Its components can relax muscles in the gut, and some capsules have a coating that delays release until they reach the intestine. Researchers study it for belly pain and other symptoms of irritable bowel syndrome. Evidence supports some short-term symptom relief, but it can cause heartburn.

Technical definition

Peppermint oil is a volatile botanical oil distilled from Mentha × piperita, composed primarily of monoterpenes such as menthol and menthone; enteric-coated formulations delay release until the intestine. Menthol activates TRPM8 cold-sensitive ion channels, while inhibition of calcium influx in gastrointestinal smooth muscle contributes to antispasmodic effects. Products are regulated as supplements or herbal medicines depending on jurisdiction and formulation.

Educational information only. This page does not provide medical advice or determine whether a supplement is appropriate for you. Review supplements with a qualified healthcare professional, especially if you take medication, are pregnant, have surgery scheduled, or have a chronic medical condition.

Evidence by use

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    Complete Research Guide

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    Overview

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    Structure & Properties

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    How It Works

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    Human Research

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    Laboratory Research

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    Administration & Studied Formulations

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    Applications & Related Therapies

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    Cases, Considerations & Ethics

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    References

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      Educational reference only. Not medical advice. Consult a qualified clinician before starting any peptide protocol.

      Non-FDA-approved peptides are for research use only. Not for human or animal consumption.