Pomegranate extract
Also known as punica granatum, punicalagin, pomegranate.
Last reviewed October 9, 2026 · Jump to references
What is Pomegranate extract?
In plain words
Pomegranate extract is a concentrated preparation made from parts of the pomegranate fruit. Gut bacteria turn some of its plant compounds into smaller substances that the body can absorb, though this varies from person to person. Researchers study it for possible effects on blood pressure, blood vessel health, and inflammation. Human studies have shown mixed results, so its health benefits are not firmly established.
Technical definition
Pomegranate extract is a botanical preparation derived from Punica granatum fruit components, containing variable amounts of polyphenols such as the ellagitannins punicalagins and ellagic acid. Ellagitannins can release ellagic acid, which intestinal microbes convert into urolithins; these compounds are studied for effects on oxidative stress and inflammatory signaling rather than action at a single established receptor. Pomegranate extract is marketed as a dietary supplement in the United States and is not FDA-approved to treat or prevent disease.
Educational information only. This page does not provide medical advice or determine whether a supplement is appropriate for you. Review supplements with a qualified healthcare professional, especially if you take medication, are pregnant, have surgery scheduled, or have a chronic medical condition.
Evidence by use
Each use is rated on its own. There is no single overall effectiveness score.
Complete Research Guide
Open each section for the available evidence. Gaps are stated rather than inferred.
Overview
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Structure & Properties
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How It Works
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Human Research
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Laboratory Research
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Processing & Interactions
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Safety & Precautions
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Administration & Studied Formulations
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Applications & Related Therapies
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Cases, Considerations & Ethics
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