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GHRP-6
Research Use
Also known as Growth Hormone Releasing Peptide-6
Function
Primary
GH secretagogue · Appetite stimulation
Secondary
Body composition
Mechanism
GHS-R1a agonist — stimulates GH release; pronounced ghrelin-like appetite stimulation; gastroprotective properties.
Evidence
Pre-clinical / Observational
Research
Pre-clinical and observational; limited Phase I
Dosing
Range
100–300 mcg/dose
Frequency
1–3× daily
Route
Subcutaneous
Administration & Technique
Subcutaneous (SubQ)
Default route for most research and therapeutic peptides — best absorption for reconstituted powder.
Device31G × 5/16" insulin syringe (U-100). 100 units = 1 mL.
TechniquePinch skin at abdomen (2" from navel), outer thigh, or love handle. Insert at 45–90°. Rotate sites daily to prevent lipohypertrophy. Alcohol-swab site, air-dry, inject slow, hold 5 sec.
Injection & Application Sites
Front
Back
Subcutaneous (SubQ)
- Abdomen — 2 in (5 cm) away from the navel, either side. Fastest, most consistent SubQ absorption.
- Flank / love handle — Lateral fat pad above the hip. Good rotation site when the abdomen is tender.
- Outer thigh — Upper outer quadrant, a hand-width below the hip. SubQ pinch at 45°.
Diagram is a general illustration, not a medical instruction. Rotate sites every injection, keep 1 in (2.5 cm) between recent sites, and avoid scars, moles, bruises and the navel area.
Cycling
8–12 weeks on / 4 weeks off.
Timing & Interactions
When to take
2–3× daily fasted. Strong appetite stimulation — avoid pre-sleep if weight loss is a goal.
Do not combine with
- ·Ipamorelin, GHRP-2, Hexarelin — same class
- ·MK-677
Complements
- ·Mod GRF 1-29 / CJC-1295 for GH synergy
Storage & Reconstitution
Powder (Pre-Reconstitution)
Lyophilized powder: refrigerate 2–8°C for up to 24 months, or freeze at –20°C for extended storage. Keep sealed, desiccated, and protected from light.
After Reconstitution
After reconstitution with bacteriostatic water, refrigerate at 2–8°C and use within 28 days. Discard if cloudy, discolored, or precipitated.
Notes
Do not freeze after reconstitution — freeze/thaw cycles degrade most peptides.
Reconstitution Calculator
Concentration
2.50 mg/mL
Volume per dose
0.100 mL
Insulin syringe
10.0 units (U-100)
1 mL = 100 units on a standard U-100 insulin syringe. Draw to the nearest 0.5 unit and confirm dosing with a clinician before injection.
Your Notes
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Benefits
- ·Appetite support in wasting states
- ·GH release
- ·Gastroprotective in models
Risks
- ·Strong hunger stimulation
- ·Cortisol and prolactin elevation
- ·Desensitization
Contraindications
- ·Active malignancy
- ·Pregnancy
Regulatory
Not FDA-approved; research use
Veterinary Use (Pets)
No established veterinary protocol for GHRP-6. Consult a licensed veterinarian before considering off-label use in any species.
Full veterinary reference →Functional Groups
Cited Works
- Locatelli V, Torsello A. GHRP-6 review. Curr Pharm Des. 2004;10:2255.