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P21
Research Use
Also known as Cerebrolysin-derived neurogenic peptide
Function
Primary
Neurogenesis (research) · Cognitive support
Mechanism
CNTF-mimetic peptide derived from Cerebrolysin pharmacology — stimulates hippocampal neurogenesis and dendritic arborization.
Evidence
Pre-clinical / Observational
Research
Pre-clinical rodent studies
Dosing
Range
Research dosing only
Frequency
Variable
Route
Subcutaneous · Intranasal (research)
Cycling
Not established.
Benefits
- ·Promotes neurogenesis
- ·Improves rodent learning/memory
- ·Potential synergy with Cerebrolysin
Risks
- ·No human safety data
- ·Unknown PK
Contraindications
- ·Pregnancy
- ·Active malignancy
Regulatory
Research peptide — not approved
Functional Groups
Cited Works
- Plata-Salaman CR et al. P21 (Cerebrolysin-derived) — neurogenesis review. CNS Drug Rev. 2007.