← Library
LL-37 (Cathelicidin)
Research Use
Also known as hCAP18 peptide
Function
Primary
Antimicrobial · Wound healing
Secondary
Immunomodulation
Mechanism
Human cathelicidin antimicrobial peptide — disrupts bacterial membranes; modulates TLR signaling; promotes keratinocyte migration; anti-biofilm.
Evidence
Pre-clinical / Observational
Research
Pre-clinical and in vitro primarily
Dosing
Range
Not standardized for human use
Frequency
Variable
Route
Topical · Intralesional (research)
Cycling
Not standardized.
Benefits
- ·Broad antimicrobial activity
- ·Wound healing in models
- ·Biofilm disruption
Risks
- ·Pro-inflammatory at high doses
- ·Potential oncogenicity in some cancer models
Contraindications
- ·Active malignancy (theoretical)
- ·Pregnancy
Regulatory
Not FDA-approved; research use
Functional Groups
Cited Works
- Vandamme D et al. A comprehensive summary of LL-37. Cell Immunol. 2012;280:22.source