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CJC-1295 (no DAC / Mod GRF 1-29)
Research Use
Also known as Mod GRF 1-29, CJC-1295 no DAC
Function
Primary
Physiologic GH pulse amplification
Secondary
Anti-aging · Sleep quality
Mechanism
Short-acting GHRH analog (t½ ~30 min) — preserves pulsatile GH secretion; often combined with Ipamorelin for synergy.
Evidence
Pre-clinical / Observational
Research
Pre-clinical and observational only
Dosing
Range
100–300 mcg/dose
Frequency
2–3× daily or before sleep
Route
Subcutaneous
Administration & Technique
Subcutaneous (SubQ)
Default route for most research and therapeutic peptides — best absorption for reconstituted powder.
Device31G × 5/16" insulin syringe (U-100). 100 units = 1 mL.
TechniquePinch skin at abdomen (2" from navel), outer thigh, or love handle. Insert at 45–90°. Rotate sites daily to prevent lipohypertrophy. Alcohol-swab site, air-dry, inject slow, hold 5 sec.
Injection & Application Sites
Front
Back
Subcutaneous (SubQ)
- Abdomen — 2 in (5 cm) away from the navel, either side. Fastest, most consistent SubQ absorption.
- Flank / love handle — Lateral fat pad above the hip. Good rotation site when the abdomen is tender.
- Outer thigh — Upper outer quadrant, a hand-width below the hip. SubQ pinch at 45°.
Diagram is a general illustration, not a medical instruction. Rotate sites every injection, keep 1 in (2.5 cm) between recent sites, and avoid scars, moles, bruises and the navel area.
Cycling
8–12 weeks on / 4 weeks off.
Timing & Interactions
When to take
2–3× daily on an empty stomach — typical schedule is post-workout, mid-day, and 30 min pre-bed. Avoid food (fats/carbs) 30 min before and after each dose to preserve the GH pulse.
Do not combine with
- ·CJC-1295 with DAC — same class, do not stack
- ·Tesamorelin — redundant GHRH activity
- ·Food or alcohol within 30 min of dosing
Complements
- ·Ipamorelin or GHRP-2 — classic GHRH + GHRP synergy
- ·BPC-157 for injury cycles
Storage & Reconstitution
Powder (Pre-Reconstitution)
Lyophilized powder: refrigerate 2–8°C for up to 24 months, or freeze at –20°C for extended storage. Keep sealed, desiccated, and protected from light.
After Reconstitution
After reconstitution with bacteriostatic water, refrigerate at 2–8°C and use within 28 days. Discard if cloudy, discolored, or precipitated.
Notes
Do not freeze after reconstitution — freeze/thaw cycles degrade most peptides.
Reconstitution Calculator
Concentration
2.50 mg/mL
Volume per dose
0.100 mL
Insulin syringe
10.0 units (U-100)
1 mL = 100 units on a standard U-100 insulin syringe. Draw to the nearest 0.5 unit and confirm dosing with a clinician before injection.
Your Notes
Your Notes
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Benefits
- ·Preserves natural GH pulsatility
- ·Improved sleep and recovery (anecdotal)
- ·Synergistic with GHRPs
Risks
- ·Water retention
- ·Headache
- ·IGF-1 elevation
- ·Theoretical oncogenicity
Contraindications
- ·Active malignancy
- ·Pregnancy
- ·Severe diabetic retinopathy
Regulatory
Not FDA-approved; compounded/research use
Veterinary Use (Pets)
No established veterinary protocol for CJC-1295 (no DAC / Mod GRF 1-29). Consult a licensed veterinarian before considering off-label use in any species.
Full veterinary reference →Functional Groups
Cited Works
- Teichman SL et al. Prolonged Stimulation of GH and IGF-I Secretion by CJC-1295. J Clin Endocrinol Metab. 2006;91:799.source