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PEG-MGF
Research Use
Also known as Pegylated Mechano-Growth Factor, IGF-1Ec
Function
Primary
Muscle repair (research)
Mechanism
PEGylated splice variant of IGF-1 (MGF / IGF-1Ec) — activates muscle satellite cells in response to mechanical loading; PEGylation extends half-life.
Evidence
Pre-clinical / Observational
Research
Pre-clinical only
Dosing
Range
100–200 mcg, 2–3×/week (anecdotal)
Frequency
Post-workout / multiple weekly
Route
Subcutaneous · Intramuscular
Cycling
4–8 week cycles in user protocols.
Benefits
- ·Satellite cell activation
- ·Localized hypertrophy / repair
- ·Potential tendon repair
Risks
- ·Hypoglycemia
- ·Theoretical tumor promotion
- ·Injection-site reactions
Contraindications
- ·Cancer history
- ·Pregnancy
Regulatory
Research chemical — banned by WADA
Functional Groups
Cited Works
- Goldspink G. Mechano-Growth Factor: a target for hypertrophy & repair. J Musculoskelet Neuronal Interact. 2005;5:344.